PRP injection and home workouts show promise for Women's knee pain
NCT ID NCT07307118
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 27 women with knee osteoarthritis who received a single platelet-rich plasma (PRP) injection followed by a 6-week home exercise program. Researchers measured hip and knee strength and pain levels over 12 weeks. The goal was to see if this combination could reduce pain and improve function without surgery or daily medication.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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27 people
The number who actually took part.
- Started
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Jul 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 70 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female patients aged 45-70 years. * Radiographic knee osteoarthritis: Kellgren-Lawrence grade II-III in the affected knee and grade II or less in the unaffected knee. * Unilateral knee pain during activity with VAS score ≥5 (for at least the past 3 months). * Referred to physiotherapy following a unilateral single-dose PRP injection. Exclusion Criteria: * Any intra-articular knee injection within the past 6 months. * Regular lower-extremity strengthening exercise or non-pharmacological treatment for knee OA within the past 6 weeks. * History of lower-extremity surgery. * History of neurological, rheumatological and/or cognitive diseases. * Unable to use a telephone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fırat Üniversitesi
Elâzığ, MErkez, 23200, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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