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Proton therapy offers new hope for recurrent head and neck cancer

NCT ID NCT07635641

First seen Jun 10, 2026 · Last updated Jun 22, 2026 · Updated 2 times

Summary

This study looks at using proton therapy for people whose head and neck cancer has come back in an area already treated with radiation. Since surgery is often not possible and standard radiation can harm healthy tissues, proton therapy may deliver the radiation more precisely. Researchers will track side effects, tumor control, survival, and quality of life in 50 adults to see if this approach is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Humanitas Research Hospital

    RECRUITING

    Rozzano, Milano, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

proton therapy

What this could lead to

If successful, this study could show that proton therapy is a safer and effective option for treating head and neck cancer that comes back after prior radiation.

What could go wrong

This is a small, early observational study (50 people) with no comparison group. It is designed to gather information, not to prove a treatment works. Side effects from re-irradiation are still possible.

Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.