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New device aims to shield the brain during heart valve procedure

NCT ID NCT05873816

First seen Jan 11, 2026 · Last updated May 17, 2026 · Updated 14 times

Summary

This study tested a device called ProtEmbo that is designed to catch debris and protect the brain during a heart valve replacement procedure (TAVR) in people with severe aortic stenosis. The trial compared the device to either no protection or a different device. The goal was to see if it reduces the risk of stroke, kidney injury, or other major complications within 30 days.

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Contacts and locations

Locations

  • BayCare Health System / Morton Plant Hospital

    Clearwater, Florida, 33756, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Columbia University Medical Center / NYPH

    New York, New York, 10032, United States

  • Dresden Herzzentrum

    Dresden, 01307, Germany

  • Gdansk Uniwersyteckie Centrum Kliniczne

    Gdansk, 80-214, Poland

  • Lübeck Universitätsklinikum Schleswig-Holstein Campus

    Lübeck, 23562, Germany

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Morristown Medical Center

    Morristown, New Jersey, 07690, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • NYU Langone

    New York, New York, 10016, United States

  • Saint Luke's Hospital of Kansas City

    Kansas City, Missouri, 64111, United States

  • State University of New York at Buffalo

    Buffalo, New York, 14203, United States

  • Trier Krankenhaus der Barmherzigen Brüder

    Trier, 54292, Germany

  • Tucson Medical Center Health

    Tucson, Arizona, 85712, United States

  • Ulm Universitätsklinikum

    Ulm, 89081, Germany

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Texas, Memorial Hermann Hospital

    Houston, Texas, 77030, United States

  • University of Virginia, Charlottesville

    Charlottesville, Virginia, 22908, United States

  • Washington University - St. Louis

    St Louis, Missouri, 63110, United States

  • Weill Medical College / Cornell University

    New York, New York, 10065, United States

Conditions

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