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Plant or milk protein: which boosts muscle in seniors?

NCT ID NCT06403137

Knowledge-focused Sponsor: Maastricht University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether daily protein supplements (from plants or milk) can help healthy older adults build and maintain muscle, especially when combined with exercise. Fifty-one participants aged 60-80 received either a plant protein blend, milk protein, or a placebo, along with a controlled diet and some leg exercises. The goal was to measure muscle protein synthesis rates to see if these supplements offer a benefit over a standard diet alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
plant protein blend, milk protein supplement, maltodextrin supplement
What this could lead to
If successful, this could show that plant-based protein supplements are a viable alternative to milk protein for supporting muscle maintenance in older adults.
What could go wrong
This is a small, completed study (51 participants) measuring short-term muscle protein synthesis, not long-term muscle mass or strength. Results may not apply to less healthy or younger populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

51 people

The number who actually took part.

Started

Jun 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female sex * Aged between 60 and 80 y inclusive * BMI between 18.5 and 30 kg/m2 Exclusion Criteria: * Following a self-reported vegetarian and vegan diet the 6 months prior to the study. * Intolerant to milk products * Corn allergy * Pea allergy * Participating currently or in the 3 months prior to the study in a structured (progressive) exercise program. * Smoking regularly (i.e. \>5 cigarettes/week) * History of cardiovascular, respiratory, gastrointestinal, urogenital, neurological, psychiatric, dermatologic, musculoskeletal, metabolic, endocrine, haematological, immunologic disorders, allergy, major surgery and/or laboratory assessments which might limit participation in or completion of the study protocol, interfere with the execution of the experiment, or potential influence the study outcomes (to be decided by the principal investigator and responsible physician) * Diagnosed with phenylketonuria (PKU) * Uncontrolled hypertension (blood pressure above 160/100 mmHg) * Donated blood 3 months prior to test day * Use of any medications that interferes with study participation and/or outcomes (i.e. corticosteroids, non-steroidal anti-inflammatories, gastric acid suppressing medication) as assessed by the responsible medical doctor. * Use of DOAC, vitamin-K-antagonist, or multiple anticoagulants * Pregnancy

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Conditions

The condition(s) this trial relates to.

kwashiorkor muscular atrophy protein-energy malnutrition Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Protein malnutrition Sarcopenia Skeletal muscle atrophy

Contacts and locations

Locations

  • Maastricht University Medical Center+

    Maastricht, Limburg, 6229ER, Netherlands

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