Protein showdown: which drink helps seniors most?
NCT ID NCT06956131
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at how different protein drinks (casein, whey, and soy) affect blood and urine markers in healthy older adults aged 60 to 80. Researchers will also check cognitive function, mood, and appetite after each drink. The goal is to understand how protein sources influence metabolism, which could guide future dietary recommendations for healthy aging.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Protein drinks (casein, whey, soy) and maltodextrin
- What this could lead to
- If successful, this study could help shape better dietary advice for older adults to support healthy aging.
- What could go wrong
- This is a small, early-stage study with only 32 participants, so findings may not apply to everyone. It looks at short-term changes, not long-term health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 32 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * English-literate and able to give informed consent * Adults 60 to 80 years old (inclusive) * (If applicable) Postmenopausal * BMI of 18·5 to 30 kg/m2 (inclusive) Exclusion Criteria: * Currently participating in another clinical study that involves altering the regular diet and/or involves consuming a dietary supplement or investigated food product as an intervention * Weight change \>3 kg in the past 3 months * Exercising vigorously over the past 3 months (i.e., engaging in high-intensity exercises for more than 3 hours a week, where high-intensity exercises leave one out of breath and unable to talk or sing during the workout) * Current smokers or have quit smoking for less than 5 years * Drinking \>2 alcoholic drinks per day (i.e., one drink is defined as either 150 ml of wine, 340 ml of beer/cider or 45 ml of distilled spirit) * If drinking ≤2 alcoholic drinks per day, not willing to stop consumption of alcoholic beverages two days before and on the day of the test visits (total 12 days) * Not willing to stop consumption of caffeinated beverages 10 to 12 hours before and on the day of the test visits (total 4 days) * Taking supplements containing omega-3, magnesium, gamma-aminobutyric acid (GABA), L-theanine, melatonin and/or 5-hydroxytryptophan for the past 3 months, and not willing to discontinue usage 3 months before and during the study duration * Currently on a specialised diet (e.g., vegetarian, vegan, weight loss diet) * Had serious food allergies in the past, or having intolerance, sensitivities or allergies to any of the following: milk/dairy products (e.g., casein, whey), starch/starch-derived products (e.g., rice, corn, wheat, potato), soy/soy-derived products, gluten, eggs, nuts, peanuts, fish and crustaceans. * Disease or impairment of the kidney and/or liver * Currently diagnosed with diabetes, sleep disorders, gastrointestinal issues (e.g., lactose intolerance, irritable bowel syndrome), gout and/or G6PD deficiency * History of diseases known to affect the central nervous system (e.g., heart disease, stroke, migraine headaches, multiple sclerosis, Parkinson's disease, mental illnesses) * Taking antibiotics 2 weeks prior to study participation * Taking medication known to interfere with cognitive function and mental wellbeing (e.g., benzodiazepines, antidepressants, other central nervous agents) * Taking anti-hypertensive or cholesterol-lowering drugs for less than 3 years unless medically declared by an official doctor to be in stable condition * Poor peripheral venous access based on past experiences with blood drawing
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07
Singapore, 117550, Singapore
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