Proton beam boost: could fewer sessions mean better prostate cancer control?
NCT ID NCT04486755
First seen May 13, 2026 · Last updated Jun 20, 2026 · Updated 5 times
Summary
This early-phase trial tests whether giving higher doses of radiation to the prostate in fewer sessions (while also treating pelvic lymph nodes) is safe for men with intermediate- to high-risk prostate cancer. The study enrolls 18 adults and uses proton beam therapy delivered four days per week. The main goal is to find a schedule that limits severe short-term side effects like bowel, bladder, or nerve problems.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Maryland Proton Treatment Center
Baltimore, Maryland, 21201, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hypofractionated proton beam radiation therapy
What this could lead to
If successful, this could lead to a shorter, more convenient radiation schedule that delivers a stronger dose to the prostate while keeping side effects manageable.
What could go wrong
This is a very early phase 1 trial with only 18 participants, so results may not apply to all patients. The higher radiation dose could increase the risk of bowel, bladder, or nerve side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.