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New drug combo aims to shrink High-Risk prostate tumors before surgery

NCT ID NCT05726292

First seen Apr 06, 2026 · Last updated May 25, 2026 · Updated 13 times

Summary

This study tests whether adding the drug relacorilant to standard hormone therapy and enzalutamide can better shrink high-risk prostate cancer before surgery. About 90 men with advanced, localized prostate cancer that hasn't spread will take the drug combination or a placebo for 24 weeks, then have their prostate removed. The goal is to see if the new combo leads to fewer cancer cells remaining after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Comprehensive Cancer Center

    RECRUITING

    Chicago, Illinois, 60453, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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