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Early test of new drug combo for tough prostate cancer

NCT ID NCT05999968

Summary

This small, early-stage study tested the safety of combining two drugs, abemaciclib and darolutamide, in men with advanced prostate cancer that had spread and stopped responding to standard hormone therapy. The main goal was to see if the combination was safe and tolerable for patients. Researchers also looked for early signs that the treatment might help slow the cancer's growth.

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Contacts and locations

Locations

  • Highlands Oncology Group

    Springdale, Arkansas, 72762, United States

  • Hospital General Universitario Gregorio Marañon

    Madrid, Madrid, Comunidad de, 28009, Spain

  • Hospital Infanta Cristina

    Badajoz, 06006, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, Comunidad de, 28041, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, Madrid, Comunidad de, 28034, Spain

  • Hospital Universitario Virgen Del Rocio

    Seville, 41013, Spain

  • Instituto Catalan de Oncologia - Hospital Duran i Reynals

    L'Hospitalet de Llobregat, Catalunya [Cataluña], 8907, Spain

  • Klinikum Rechts Der Isar Der Technischen Universität München

    Munich, Bavaria, 81675, Germany

  • Laura and Isaac Perlmutter Cancer Center

    New York, New York, 10016, United States

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island

    Mineola, New York, 11501, United States

  • Studienpraxis Urologie

    Nürtingen, Baden-Wurttemberg, 72622, Germany

  • Universitaetsklinikum Hamburg-Eppendorf

    Hamburg, 20246, Germany

  • Universitätsklinikum Schleswig-Holstein

    Lübeck, Schleswig-Holstein, 23538, Germany

Conditions

Explore the condition pages connected to this study.