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Bee glue and sound waves: new hope for diabetic wounds?

NCT ID NCT07099482

Disease control Sponsor: Sinai University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This study tests whether using ultrasound to push propolis (a natural bee product) into the skin can help heal diabetic foot ulcers faster. Eighty adults with diabetes and foot ulcers will either get propolis plus ultrasound or standard wound care for 4 weeks. The goal is to see if the combination reduces wound size and improves healing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Propolis gel (10%) applied with therapeutic ultrasound (phonophoresis)
What this could lead to
If it works, this could offer a new, natural way to speed up healing of diabetic foot ulcers and reduce complications.
What could go wrong
This is a small, early-stage trial with only 80 participants. The treatment may not work better than standard care, and propolis could cause allergic reactions in some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Adults aged 18 to 75 years Diagnosed with type 1 or type 2 diabetes mellitus Presence of a diabetic foot ulcer classified as Grade 1 or 2 (Wagner classification) Ulcer size between 1 cm² and 5 cm² Able and willing to provide informed consent Exclusion Criteria: Severe infection or presence of osteomyelitis at the ulcer site Use of systemic immunosuppressants or corticosteroids Known allergy or hypersensitivity to propolis Pregnant or breastfeeding women Participation in another clinical trial within the past 30 days

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus type 2 diabetes mellitus ulcer of lower limbs

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic wound healing Diabetic foot ulcer T Type 1 diabetes mellitus Type 2 diabetes mellitus Wound management

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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