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Bee glue to the rescue? propolis ointment tested for dry skin

NCT ID NCT07618234

Symptom relief Sponsor: Manara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether ointments made from propolis, a natural substance from honeybees, can improve dry, itchy skin in adults with atopic tendencies. Thirty participants will apply either a propolis ointment or a plain base ointment twice daily for four weeks. Researchers will measure changes in skin dryness, scaling, and itching to see if propolis offers any benefit over the base ointment alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
propolis ointment (3% ethanolic extract or 5% crude propolis)
What this could lead to
If it works, this could point toward a natural, over-the-counter option for managing dry, itchy skin in people with atopic tendencies.
What could go wrong
This is a very small, early exploratory study with only 30 participants. The results may not apply to everyone, and propolis can cause allergic reactions in some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Apr 2026

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-60 years * Atopic-prone dry skin or mild xerotic skin condition * Mild-to-moderate skin dryness, scaling, roughness, and mild itching * No acute inflammatory skin disease * Ability to attend follow-up visits and comply with application instructions * Signed informed consent form Exclusion Criteria: * Known allergy to propolis, honey, or bee products * Known allergy to lanolin * Acute eczema flare, infected dermatitis, psoriasis, seborrheic dermatitis, fungal infections, herpes simplex, or scabies * Pregnancy or breastfeeding * Recent use of systemic corticosteroids (within 2 weeks) * Recent use of immunosuppressants (within 4 weeks) * Recent use of biologics (within 3 months) * Recent use of topical corticosteroids (within 1 week) * Recent use of topical calcineurin inhibitors (within 1 week) * Recent phototherapy (within 2 weeks) * Severe systemic diseases not under control * Poor compliance or inability to cooperate * Use of other skin products during the study period

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atopic dermatitis Dry skin Xerosis due to atopic dermatitis

Contacts and locations

Locations

  • Manara University, Faculty of Pharmacy

    Latakia, Syria

More trials for these conditions

Other studies related to the condition(s) this trial covers.