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Which anesthesia is safer for lung biopsies? new study compares two common drugs

NCT ID NCT07338578

Knowledge-focused Sponsor: Saglik Bilimleri Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study looked at 102 adults undergoing a lung biopsy (EBUS-TBNA) under general anesthesia. Researchers compared two drugs—propofol (given through a vein) and sevoflurane (inhaled as a gas)—to see which one keeps the heart and blood pressure more stable and makes the doctor's job easier. The goal is to find the best anesthesia for this procedure to improve safety and comfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
propofol and sevoflurane
What this could lead to
If this study shows one drug is better, it could help doctors choose the safest anesthesia for lung biopsies, improving patient safety and procedure quality.
What could go wrong
This is a small, completed study with only 102 participants. The results may not apply to all patients or settings, and the drugs have known side effects like low blood pressure or breathing issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

102 people

The number who actually took part.

Started

Sep 2023

Finished

Apr 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of adult patients who underwent endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) under general anesthesia at a tertiary training and research hospital. All participants were scheduled for diagnostic bronchoscopy for evaluation of pulmonary or mediastinal lesions. Patients with American Society of Anesthesiologists (ASA) physical status I-III were included.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (\> 18 years) with an ASA physical status I-III who provided written informed consent were included. Exclusion Criteria: * ASA ≥ IV * chronic cough or dyspnea * preoperative desaturation (SpO₂ \< 90%) * hypotension (MAP \< 60 mmHg), * bradycardia (HR \< 60 bpm), * hypersensitivity to anesthetics, * any form of organ failure, * laboratory abnormalities (electrolyte imbalance, anemia, polycythemia, thrombocytosis, leukopenia, or leukocytosis), * perioperative hypo- or hyperthermia, dehydration, or overhydration.

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Conditions

The condition(s) this trial relates to.

lung disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Complication of anesthesia Hemodynamic stability Pulmonary diseases or conditions

Contacts and locations

Locations

  • University of Health Sciences, Sultan 2. Abdulhamid Han Training and Research Hospital

    Istanbul, Uskudar, 34668, Turkey (Türkiye)

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