Blood test showdown: which marker best spots cancer comeback?
NCT ID NCT02556281
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 216 people with stage II or III colorectal cancer who had surgery to remove their tumor. Researchers compared two blood tests—one that looks for tumor DNA and another that looks for tumor cells—to see which better predicts if the cancer will come back within two years. No new treatment was given; the goal was simply to learn which test is more accurate.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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216 people
The number who actually took part.
- Started
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Oct 2012
- Finished
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Jun 2019
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female, age superior to 18 years. * Histologically confirmed colonic or rectal adenocarcinoma. * stage II or III (TNM classification). * Curative resection (R0) * Absence of metastasis (abdominal ultrasonography or CTscan and pulmonary Rx or CTscan) in exams performed within 4 weeks. * ECOG performance status \<3. * Signed and dated informed consent document. Exclusion Criteria: * Metastatic disease. * Familial adenomatous polyposis * Prior chemotherapy and or radiotherapy within 6 weeks * Medical history of cancer within 5 years except: basocellular cutaneous neoplasia and intraepithelial neoplasia of the cervix
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Rouen University Hospital
Rouen, 76031, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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