Hormone showdown: which progestin best tames uterine cancer before surgery?
NCT ID NCT07436793
First seen Feb 28, 2026 · Last updated Jun 09, 2026 · Updated 16 times
Summary
This study compares two hormone drugs (megestrol acetate and micronized progesterone) in 140 women with endometrial cancer or precancer. Participants take one of the drugs for a short time before their scheduled surgery. Researchers will measure how well each drug slows cancer cell growth and look for clues about why one might work better. The goal is to improve hormone therapy for this type of cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, 52242, United States
Contact Email: •••••@•••••
Contact
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University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Utah Sugarhouse Health Center
Salt Lake City, Utah, 84106, United States
Contact Email: •••••@•••••
Contact
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908, United States
Contact Email: •••••@•••••
Contact
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.