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Blood test may speed up sepsis treatment in ICUs

NCT ID NCT06958354

Knowledge-focused Sponsor: Gulhane Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 1,529 intensive care patients with sepsis to see if a blood marker called procalcitonin (PCT) can help identify the type of bacteria causing the infection. Researchers measured PCT levels within 24 hours of a positive blood culture. The goal was to see if PCT levels differ between Gram-positive, Gram-negative, and fungal infections, which could help doctors choose the right antibiotics sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors choose the right antibiotics faster for ICU patients with sepsis.
What could go wrong
This is an observational study, not a treatment trial. The results may not change practice directly, and procalcitonin levels can be influenced by other conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,529 people

The number who actually took part.

Started

Mar 2023

Finished

Oct 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Among the patients who were followed up in the intensive care unit between 01.01.2018 and 01.01.2023 and who were found to have a positive blood culture during their follow up, only those whose PCT results were obtained within 24 hours, based on the time the blood culture sample was taken, will be included.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Positive blood culture during their follow up * Patients over 18 years of age Exclusion Criteria: * Those under the age of 18 * Those who have had surgery or trauma in the last 72 hours * Those with a history of autoimmune disease, chronic renal failure * Patients admitted to intensive care due to acute pancreatitis, pregnancy, burns. * Patients with incomplete data.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis infectious disease with sepsis Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bacteremia and sepsis Intensive care medicine Procalcitonin Sepsis SEPTIC

Contacts and locations

Locations

  • Gulhane Training and Research Hospital

    Ankara, Türkiye, 06010, Turkey (Türkiye)

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