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Could probiotics soothe reflux? new study begins

NCT ID NCT07600008

First seen May 22, 2026 · Last updated Jun 19, 2026 · Updated 7 times

Summary

This early-stage trial is testing whether a probiotic supplement can improve gut health and reduce symptoms in people with gastroesophageal reflux disease (GERD) who are already taking standard acid-reducing medication. Fifty participants will receive either the probiotic or a placebo for six weeks. Researchers will measure changes in gut and mouth bacteria, symptom scores, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital Olomouc

    RECRUITING

    Olomouc, 77900, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

probiotic dietary supplement (Lactobacillaceae, Streptococcus, Bifidobacterium)

What this could lead to

If it works, this could point toward a simple probiotic supplement to help manage GERD symptoms alongside standard medication.

What could go wrong

This is a very early, small trial (50 people) testing a dietary supplement, not a drug. It may show no benefit over placebo, and results may not apply to all GERD patients.

Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.