Probiotic cocktail cuts diarrhea duration in young kids
NCT ID NCT07342088
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a mix of two probiotics (Lactobacillus acidophilus and Limosilactobacillus reuteri) could shorten diarrhea in children aged 1 to 6 with acute infectious diarrhea. 145 children were randomly assigned to receive the probiotics or a placebo. Researchers measured how long diarrhea lasted and tracked gut bacteria changes. The goal was to see if these friendly bacteria could ease symptoms and speed recovery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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145 people
The number who actually took part.
- Started
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May 2024
- Finished
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Apr 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 year to 6 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 1-6 years * Clinical diagnosis of acute infectious diarrhea * Presentation within 24 hours of symptom onset * Mild or no dehydration * Written informed consent from parents or guardians Exclusion Criteria: * Antibiotic or probiotic use within the previous month * Moderate or severe dehydration * Malnutrition * Immunosuppression * Chronic systemic disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sancaktepe Ilhan Varank Research and Training Hospital, University of Health Sciences,
Istanbul, Turkey (Türkiye)
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