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Could probiotics shield ICU patients from deadly infections?

NCT ID NCT07164781

First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 35 times

Summary

This study tests whether giving probiotics (Bacillus clausii) to critically ill adults can reduce infections like pneumonia, bloodstream infections, and UTIs. One hundred ICU patients will receive either the probiotic or a sugar pill. The main goal is to see if probiotics lower the number of systemic infections.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Benha University Hospitals

    Banhā, Qalyubia Governorate, 13518, Egypt

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bacillus clausii (a type of probiotic)

What this could lead to

If it works, this could point toward a simple, low-cost way to lower infection rates in intensive care patients.

What could go wrong

This is a small, early-stage trial (100 patients) with no phase designation. Probiotics may not prevent infections, and results may not apply to all ICU patients.

Conditions

The condition(s) this trial relates to.

diarrheal disease Pneumonia, Ventilator-Associated Toxemia urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.