Probiotic powder may tame blood sugar in Pre-Diabetes
NCT ID NCT06972524
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a special probiotic supplement, taken daily for 8 weeks, can improve blood sugar control in middle-aged and older adults with pre-diabetes. About 110 participants will receive either the probiotic powder or a placebo. Researchers will measure changes in fasting blood sugar, blood sugar after a meal, and time spent in a healthy blood sugar range.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a special probiotic supplement containing multiple ingredients (e.g., Paracaseobacterium LC19, Bifidobacterium lactis, mulberry leaf extract, bitter melon powder) mixed with milk powder
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help manage blood sugar in people with pre-diabetes, potentially delaying or preventing diabetes.
- What could go wrong
- This is a small, early-stage trial (110 participants) over only 8 weeks, so results may not be generalizable. The supplement is a mix of many ingredients, making it unclear which one works, and benefits may be modest or absent.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 110 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Dec 2025
An estimate. Start dates often move.
- Expected to finish
-
Jun 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age between 40 and 75 years, regardless of gender. 2. Impaired fasting glucose (5.6 mmol/L ≤ FPG \< 6.9 mmol/L) or glycated hemoglobin (HbA1c) between 5.7-6.4% (39-47 mmol/mol). 3. Resided in Guangzhou for the past six months and no plans to relocate or travel outside the city in the next month. 4. Signed informed consent form and voluntarily agreed to participate in the project. Exclusion Criteria: 1. Patients with a confirmed diagnosis of diabetes who are currently taking glucose-lowering medications (e.g., insulin, GLP-1 receptor agonists, or SGLT2 inhibitors). 2. Individuals with lactose intolerance or dairy product intolerance. 3. Pregnant, planning to become pregnant within the next three months, or currently breastfeeding. 4. Weight change \> 5% in the past three months or plans to lose weight or change dietary habits. 5. Alcohol consumption \> 40g/day. 6. Individuals with communication barriers, cognitive impairments, or other conditions that may prevent them from completing the study procedures. 7. Severe diseases that may affect participation in the study, including but not limited to endocrine disorders, severe cardiovascular or cerebrovascular diseases, cancer, metabolic diseases, etc. 8. Participation in or current involvement in other clinical trials within the past three months. 9. No use of antibiotic medications within the past three months.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Pre-biabetes are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.