Gut health breakthrough: probiotics may boost anemia treatment in dialysis patients
NCT ID NCT07296146
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking probiotics daily can help chronic kidney disease patients on dialysis better respond to anemia medication (erythropoietin). About 80 adults will receive either erythropoietin alone or erythropoietin plus probiotics for 3 months. Researchers will track hemoglobin levels and symptom diaries to see if probiotics reduce resistance to treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients with end stage renal disease for more than 3 months on regular hemodialysis (GFR less than 15 ml/min/m2 * Receiving stable doses of erythropoietin therapy * Able and willing to provide informed consent Exclusion Criteria: * Recent probiotic, antibiotic, or immunosuppressive therapy * Microcytic hypochromic anemia. * Patients with hyperparathyroidism * Recent or planned kidney transplantation Gastrointestinal disorders (active IBD, cancer) * Pregnancy or lactation * Severe comorbidities (e.g., active infection, malignancies) * Cognitive or physical inability to comply with protocol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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