Probiotic pill may fight gum problems for people with braces
NCT ID NCT06752330
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 33 times
Summary
This study tested whether taking a daily probiotic (Bifidobacterium Lactis HN019) can reduce plaque buildup and gum bleeding in people undergoing orthodontic treatment with braces or clear aligners. Sixty participants, aged 10 to 30, took the probiotic or a placebo for a period while researchers measured gum health. The goal was to see if this simple addition to oral hygiene could help prevent common dental issues during orthodontic care.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AOU Città della Salute e della Scienza
Torino, Italy, 10126, Italy
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bifidobacterium Lactis HN019 probiotic (with Kluyveromyces Marxianus Fragilis B0399, colostrum, and biotin)
What this could lead to
If it works, this could point toward a simple way to improve gum health during orthodontic treatment.
What could go wrong
This is a small, completed trial with only 60 participants, so results may not apply to everyone. The effect on plaque and bleeding may be modest or not clinically significant.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.