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Can a probiotic soothe your tummy troubles?

NCT ID NCT07618026

Symptom relief Sponsor: Colorado State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a probiotic called Bacillus clausii (Munispore) can improve mild-to-moderate stomach issues in healthy adults. Fifty-five participants took either the probiotic or a placebo in a crossover design. Researchers tracked gut symptoms, inflammation, and gut bacteria changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Bacillus clausii probiotic (Munispore)
What this could lead to
If it works, this could point toward a simple probiotic supplement to reduce everyday gut discomfort.
What could go wrong
This is a small, completed trial with only 55 participants. The effect may be small or not apply to everyone. Probiotics can sometimes cause bloating or gas.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

55 people

The number who actually took part.

Started

Mar 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-75 * BMI 18-34.9 * self report as healthy * consistent Mild to Moderate gastrointestinal distress (determined by a functional GI screen) Exclusion Criteria: * \<18 or \>75 * BMI \<18 or \>34.9 * antibiotics within two months * probiotic/prebiotic supplements within two weeks prior to the screening process * pregnant or breastfeeding * taking medications that influence study endpoints of the study (i.e., statins, metformin, nonsteroidal anti-inflammatory drugs, and monoamine oxidase inhibitors) * a current diagnosis of cancer, liver or kidney disease, metabolic disorders, and GI diseases (Celiac disease, inflammatory bowel disease, and peptic ulcer disease)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gastrointestinal health

Contacts and locations

Locations

  • Food and Nutrition Clinical Research Laboratory

    Fort Collins, Colorado, 80523, United States

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