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Enzyme cocktails aim to soothe tummy troubles

NCT ID NCT06710392

Symptom relief Sponsor: The Archer-Daniels-Midland Company Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether two enzyme blends can safely ease mild to moderate stomach discomfort in healthy adults. Eighteen participants took a placebo for 4 weeks and the enzyme for 4 weeks, filling out weekly questionnaires about their gut health. The goal was to see if the enzymes improved symptoms like bloating or irregular stools.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

18 people

The number who actually took part.

Started

May 2025

Finished

Feb 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Exclusion Criteria: * Presence of a serious congenital anomaly or chronic medical condition that would contraindicate participation, including history of major gastrointestinal surgery, chronic gastrointestinal illness, abnormal intestinal anatomy or significant abdominal disorder * Having taken oral antibiotics in the previous 3-months or if they start antibiotics during the study * Currently or having taken a prebiotic, probiotic, or digestive enzyme supplement in the previous 3-months * Currently consuming 1 or more servings of fermented foods or yogurt on a daily basis * Doctor diagnosed chronic disease (i.e. Diabetes, Cardiovascular, etc.) * Doctor diagnosed immunodeficiency * Current use of doctor prescribed immunosuppressive agents (corticosteroids, methotrexate, etc.) * Pregnancy, 6 months postpartum period, or current breastfeeding * Women of childbearing age planning pregnancy during the course of the study

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Conditions

The condition(s) this trial relates to.

digestive system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Digestive Gastrointestinal health

Contacts and locations

Locations

  • The University of North Texas

    Denton, Texas, 76201, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.