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New drug targets Hard-to-Treat cancers with genetic weakness

NCT ID NCT06130553

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This study tests a new drug called AZD3470 in people with advanced solid tumors that lack a gene called MTAP. The drug is designed to block a protein these cancer cells need to grow. The trial will first find the safest dose, then see if it shrinks tumors or slows cancer growth, both alone and with other cancer medicines.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Portland, Oregon, 97239, United States

  • Research Site

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • Research Site

    RECRUITING

    Providence, Rhode Island, 02903, United States

  • Research Site

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Research Site

    RECRUITING

    Melbourne, 3000, Australia

  • Research Site

    RECRUITING

    Beijing, 100142, China

  • Research Site

    RECRUITING

    Chengdu, 610041, China

  • Research Site

    RECRUITING

    Shanghai, 200433, China

  • Research Site

    NOT_YET_RECRUITING

    Villejuif, 94805, France

  • Research Site

    RECRUITING

    Chūōku, 104-0045, Japan

  • Research Site

    RECRUITING

    Kashiwa, 227-8577, Japan

  • Research Site

    RECRUITING

    Amsterdam, 1066CX, Netherlands

  • Research Site

    RECRUITING

    Seoul, 03080, South Korea

  • Research Site

    RECRUITING

    Seoul, 06351, South Korea

  • Research Site

    RECRUITING

    Barcelona, 8035, Spain

  • Research Site

    RECRUITING

    Madrid, 28027, Spain

  • Research Site

    RECRUITING

    San Francisco, California, 94143, United States

  • Research Site

    WITHDRAWN

    West Hollywood, California, 90048, United States

  • Research Site

    RECRUITING

    New Haven, Connecticut, 06510, United States

  • Research Site

    RECRUITING

    Baltimore, Maryland, 21231, United States

Conditions

Explore the condition pages connected to this study.