Can a heart scan predict who will get better? new study aims to find out
NCT ID NCT07243119
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 180 adults newly diagnosed with heart failure and a weak heart pump. Researchers use multiple types of heart scans and tests to see if they can predict whose heart function will improve over 3-12 months. A smaller part of the study tests a higher dose of a drug (adenosine) to see if it gives clearer images during a PET scan. The goal is to better understand heart recovery and improve personalized care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Apr 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Capable and has provided written informed consent * LVEF ≤ 40% by echocardiography in connection with hospitalization for heart failure or in connection with outpatient evaluation for heart failure Exclusion Criteria: * Previous diagnosis of heart failure * Unable to understand the patient information * Pregnancy, as the study involves ionizing radiation. * Current severe valvular disease (as defined by the Danish national treatment guidelines on cardio.dk) * Atrial fibrillation with a heart rate \> 130 beats per minute during the inclusion echocardiography * Cardiac surgery within 6 months prior to inclusion * Acute exacerbation of existing chronic obstructive pulmonary disease * Severe asthma or chronic obstructive pulmonary disease with FEV1 \< 1L * any contraindication for adenosine stress testing * Severe renal failure \< 15 mL/min/1.73m² or dialysis * Advanced liver disease (Child-Pugh class C) * Endocarditis at inclusion/baseline * Isolated right-sided heart failure * Malignant disease treated with chemotherapy or radiotherapy, or expected life expectancy under 1 year
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Clinic of Cardiovascular Reseach
Herning, 7400, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which SGLT2 inhibitor wins? trial pits empagliflozin against dapagliflozin
- Can daily mindful breathing ease heart failure symptoms?
- Can a smartphone app keep heart failure patients out of the hospital?
- Can better training get doctors to talk about what matters most to dying veterans?