Could this pill unclog Alzheimer's brains? new trial underway
NCT ID NCT06182085
First seen Jan 07, 2026 · Last updated May 22, 2026 · Updated 17 times
Summary
This study tests an experimental drug called PRI-002 in 304 people with early Alzheimer's (mild cognitive impairment or mild dementia). The drug aims to break apart small toxic protein clumps in the brain that are thought to cause memory and thinking problems. Researchers will check if it is safe and whether it slows down the disease over 48 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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A-Shine, s.r.o.
Pilsen, 30100, Czechia
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AOU Policlinico Umberto I
Rome, 00161, Italy
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ASST Spedali Civili di Brescia
Brescia, 25123, Italy
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Brain Research Center Amsterdam B.V.
Amsterdam, 1081 GN, Netherlands
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Brain Research Center Den Bosch B.V.
's-Hertogenbosch, 5223 LA, Netherlands
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Brain Research Center Zwolle B.V.
Zwolle, 8025 AZ, Netherlands
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CLINTRIAL, s.r.o.
Prague, 10000, Czechia
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Charité - Universitätsmedizin
Berlin, 13125, Germany
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Clinica Neurologica Dipartimento di Neuroscienze e Imaging (CAST)
Chieti, 66013, Italy
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Euromedis Sp. z o.o., Centrum Medyczne EUROMEDIS
Szczecin, 70-111, Poland
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FORBELI s.r.o.
Prague, 14800, Czechia
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Fondazione IRCCS.Istituto Neurologico Carlo Besta
Milan, 20133, Italy
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Fondazione Policlinico Universitario A. Gemelli IRCCS
Rome, 00168, Italy
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Fundació ACE - Institut Català de Neurociències Aplicades
Barcelona, 08028, Spain
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Hospital Clínico Universitario Virgen de la Arrixaca
El Palmar, Murcia, 30120, Spain
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Hospital Universitario Doctor Peset
Valencia, 46017, Spain
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Hospital Universitario Virgen Macarena,
Seville, 41003, Spain
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Hospital Viamed Montecanal
Zaragoza, 50012, Spain
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INEP Medical s.r.o.
Prague, 18600, Czechia
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IRCCS Ospedale San Raffaele
Milan, 20132, Italy
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ISPG - Institut für Studien zur Psychischen Gesundheit
Mannheim, 68165, Germany
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Krakowska Akademia Neurologii Sp. z o.o., Centrum Neurologii Klinicznej
Krakow, 30-505, Poland
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Neuro Health Centrum ltd.
Brno, 62800, Czechia
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NeuroCor, ul. Medweciego 7/U12
Krakow, 31-870, Poland
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Neuroprotect Sp. z o.o., Centrum Medyczne NeuroProtect
Warsaw, 01-684, Poland
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Neuropsychiatrie s.r.o.
Prague, 16000, Czechia
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NeuropsychiatrieHK, s.r.o.
Hradec Králové, 50341, Czechia
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Ospedale Bellaria - IRCCS Istituto delle Scienze Neurologiche
Bologna, 40139, Italy
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Ospedale Santa Maria della Misericordia
Perugia, 06129, Italy
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Revit Sp. z o.o., Podlaskie Centrum Psychogeriatrii
Bialystok, 15-756, Poland
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Technische Universität München
München, 81675, Germany
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Uniklinik RWTH Aachen
Aachen, 52074, Germany
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University Medical Center Rostock
Rostock, 18147, Germany
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Universitätsklinikum Düsseldorf
Düsseldorf, 40225, Germany
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Universitätsklinikum Magdeburg
Magdeburg, 39120, Germany
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Universitätsklinikum Münster - Klinik für Allgemeine Neurologie
Münster, 48149, Germany
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Universitätsklinikum Ulm
Ulm, 89081, Germany
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Wielospecjalistyczne Centrum Medyczne "Ibismed" s.c.
Zabrze, 41-800, Poland
Conditions
Explore the condition pages connected to this study.