Can your own blood help erase stretch marks?
NCT ID NCT07561671
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two treatments made from patients' own blood—platelet-rich fibrin and platelet-rich plasma—with or without microneedling, to see which works better for stretch marks. Thirty adults received different treatments on each side of their body over five sessions. Researchers measured changes in stretch mark severity and patient satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Platelet-rich fibrin and platelet-rich plasma (both derived from the patient's own blood)
- What this could lead to
- If successful, this could point toward a more effective, natural treatment for reducing the appearance of stretch marks.
- What could go wrong
- This is a small, completed study with only 30 participants, so results may not apply to everyone. The treatments are cosmetic and may not work for all types of stretch marks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Feb 2024
- Finished
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Feb 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults ≥18 years * Presence of striae distensae (rubrae or alba) * Willingness to participate and provide informed consent Exclusion Criteria: * Keloid or hypertrophic scar tendency * Bleeding disorders or anticoagulant use * Pregnancy * Active skin infections (e.g., herpes, impetigo, tinea) * History of malignancy or collagen disease * Use of antineoplastic drugs * Conditions impairing wound healing * Unrealistic expectations
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Zagazig University Hospitals
Zagazig, Zagazig--, 44519, Egypt
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