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Bacterial cocktail may stop infant wheeze after bronchiolitis

NCT ID NCT05064631

First seen Nov 20, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This study tests whether an oral bacterial lysate (Broncho-Vaxom) can reduce wheezing episodes in infants who were hospitalized for severe bronchiolitis. About 173 infants will receive either the bacterial extract or a placebo for up to 24 months. The goal is to see if this treatment can prevent the development of wheeze and potentially asthma later in childhood.

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Contacts and locations

Locations

  • King's College Hospital NHS Foundation Trust

    London, SE5 9RS, United Kingdom

  • Royal London Hospital

    London, E1 1FR, United Kingdom

  • University Hospital Southampton NHS Foundation Trust

    Southampton, SO16 6YD, United Kingdom

Conditions

Explore the condition pages connected to this study.