New hope for stroke prevention in patients who Can't take blood thinners
NCT ID NCT03111654
First seen Nov 19, 2025 · Last updated Jun 19, 2026 · Updated 27 times
Summary
This study tested a procedure to close a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who had a brain bleed and cannot use standard blood thinners. The goal was to see if this could prevent future strokes without causing another bleed. Researchers followed 58 patients over time to track their health outcomes.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Amiens Picardie
Amiens, Picardie, 80054, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
percutaneous closure of the left atrial appendage
What this could lead to
If successful, this technique could offer a safe way to prevent strokes in atrial fibrillation patients who cannot take blood thinners due to a prior brain bleed.
What could go wrong
This is a small pilot study with only 58 participants, so results may not apply broadly. The procedure itself carries risks, and long-term benefits versus harms are still uncertain.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.