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New study aims to stop the burn of common anesthesia drug

NCT ID NCT07285980

Symptom relief Sponsor: Asma Ladib Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two methods using lidocaine to prevent the pain that often happens when propofol is injected before surgery. 180 adults scheduled for elective surgery were randomly assigned to receive propofol alone, propofol mixed with lidocaine, or a brief lidocaine block before propofol. The main goal was to see which approach best reduced injection pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lidocaine
What this could lead to
If successful, this could provide a simple, effective way to reduce the burning pain patients feel when receiving propofol before surgery.
What could go wrong
This is a small, completed trial with no phase designation, so results may not apply to all patients or settings. Lidocaine itself can cause rare allergic reactions or side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

180 people

The number who actually took part.

Started

Mar 2025

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older * American Society of Anesthesiologists (ASA) physical status I to III * Scheduled for elective surgery under general anesthesia requiring intravenous induction with propofol Exclusion Criteria: * Patient refusal * Known hypersensitivity to local anesthetics or propofol * Pre-existing vascular disease * Infection at the intended injection site * Chronic use of analgesics or anxiolytics * Inability to understand the pain assessment scale * History of drug abuse

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Propofol injection pain

Contacts and locations

Locations

  • Maternity and Neonatology Center of Monastir

    Monastir, Monastir Governorate, 5000, Tunisia

More trials for these conditions

Other studies related to the condition(s) this trial covers.