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New hope for hospital patients: drug may shield kidneys from toxic meds

NCT ID NCT06886464

First seen Jan 07, 2026 · Last updated May 20, 2026 · Updated 23 times

Summary

This study tests whether cilastatin, a drug already used for other purposes, can prevent acute kidney injury in hospitalized patients who must take medications known to harm the kidneys. About 700 adults receiving certain antibiotics, chemotherapy, or contrast dyes will receive either cilastatin or a placebo every 6 hours. Researchers will monitor kidney function daily and follow up at 90 days to see if the drug reduces injury.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alberta

    RECRUITING

    Edmonton, Alberta, T6G 2R3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 1N4, Canada

Conditions

Explore the condition pages connected to this study.