New drug aims to shield ears from antibiotic side effect
NCT ID NCT05730283
Summary
This study is testing a new oral drug, ORC-13661, to see if it can prevent or reduce hearing loss in patients who need to take the antibiotic amikacin for a serious lung infection. About 105 adults will take either a high dose, low dose, or a placebo pill daily while on their antibiotic treatment for up to 90 days. Researchers will compare the groups to see if the study drug helps protect hearing during this necessary but potentially harmful therapy.
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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National Jewish Health
RECRUITINGDenver, Colorado, 80206, United States
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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University of Texas Health Science Center
RECRUITINGTyler, Texas, 75708, United States
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Conditions
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