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Toothpaste, diet advice, or sealants: which best stops Kids' cavities?

NCT ID NCT06602765

Prevention Sponsor: Bahria University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests three approaches to prevent cavities in 180 children aged 6-7 in Karachi, Pakistan. One group brushes with fluoride toothpaste, another adds dietary advice, and the third also gets sealants on their back teeth. The goal is to find the most effective and affordable strategy to reduce the widespread problem of tooth decay in children.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fluoride toothpaste, dietary counselling, and fissure sealant
What this could lead to
If successful, this could identify the most effective and cost-efficient way to prevent cavities in schoolchildren, potentially reducing the burden of dental disease in low- and middle-income countries.
What could go wrong
This is a small, single-year trial in one city, so results may not apply broadly. The study is not testing a new drug or cure, and the interventions are already known to help—so the main question is which combination works best.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 180 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Nov 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 7 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Schoolchildren aged 6-7 years Sound 1st permanent molars Consent obtained from parents/guardians Cooperative Children Exclusion Criteria: 1st Permanent molar has not erupted. Children with disability. Special Children (e.g. Down syndrome)

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Conditions

The condition(s) this trial relates to.

dental caries prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Prevention of dental caries

Contacts and locations

Locations

  • Pakistan Navy Educational Trust

    Karachi, Sindh, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.