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Diabetes drug tested to shield ICU patients from kidney failure

NCT ID NCT05468203

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times

Summary

This study aimed to see if dapagliflozin, a drug used for diabetes and chronic kidney disease, could prevent acute kidney injury in critically ill patients in the intensive care unit (ICU). The plan was to enroll 3000 adults at high risk for kidney damage, giving them either the drug or a placebo daily for up to 30 days. However, the study was terminated early after only 51 participants, so no conclusions can be drawn.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

  • Epworth Richmond

    Richmond, Victoria, 3121, Australia

  • Grampians Health

    Ballarat, Victoria, 3350, Australia

Conditions

Explore the condition pages connected to this study.