Could a 1-Hour blood test replace the 3-Hour test for heart attacks?
NCT ID NCT05649384
First seen Feb 01, 2026 · Last updated Jun 22, 2026 · Updated 14 times
Summary
This study compares two ways of using blood tests to diagnose heart attacks in people arriving at the emergency room with chest pain. The standard approach measures a heart-damage marker in the blood at arrival and again 3 hours later. The newer approach does the second test after just 1 hour. Researchers want to see if the faster method is as safe and accurate, and whether it can help patients spend less time in the ER. Over 64,000 adults with chest pain will be included.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Attikon General Hospital Athens
Athens, Greece
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Azienda Ospedaliera San Giovanni Addolorata
Roma, Italy
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Baylor St. Luke's Medical Center
Houston, Texas, 77030, United States
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Careggi University Hospital Florence
Florence, Italy
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Emergency Institute for Cardiovascular Diseases C.C. Iliescu
Bucharest, Romania
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Hospital Città della Salute e della Scienza di Torino
Torino, Italy
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Hospital Clinic Barcelona
Barcelona, Spain
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Hospital Clínico Universitario Valencia
Valencia, Spain
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Kantonsspital Aarau
Aarau, Switzerland
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Kantonsspital Luzern
Lucerne, Switzerland
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Konkuk University Medical Center
Seoul, South Korea
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Royal Cornwall Hospitals Treliske
Truro, United Kingdom
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Royal London Hospital
London, United Kingdom
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St Andrew's War Memorial Hospital Brisbane
Brisbane, Australia
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St. Claraspital
Basel, Switzerland
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University Central Hospital Helsinki
Helsinki, Finland
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University Hospital October 12 Madrid
Madrid, Spain
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University Hospital Ramon y Cajal
Madrid, Spain
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University Hospital Zurich
Zurich, Switzerland
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Vienna General Hospital (AKH Wien)
Vienna, Austria
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-sensitivity cardiac troponin blood test
What this could lead to
If successful, this could show that a faster 1-hour blood test is just as safe and accurate as the standard 3-hour test for ruling out heart attacks, potentially speeding up emergency care.
What could go wrong
This is an observational study, not a treatment trial. The faster test may not be as reliable in real-world settings or for all patient groups. Results may not apply to hospitals with different equipment or practices.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.