Can training and alerts get more people on PrEP?
NCT ID NCT06334341
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers at Henry Ford Health System are testing whether a mix of provider training, electronic health record alerts, HIV risk assessments, and patient videos can increase new PrEP prescriptions in primary care. The trial enrolls primary care providers and patients who meet the criteria for PrEP. Clinics are randomly assigned to receive different combinations of these tools, and the main measure is the rate of new PrEP prescriptions at each clinic.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A package of provider and patient interventions: computer-based simulation training, electronic health record alerts, HIV risk assessment, and a PrEP informational video
- What this could lead to
- If the strategy works, it could give primary care clinics a practical way to raise PrEP prescriptions and narrow racial and ethnic gaps in HIV prevention.
- What could go wrong
- The trial tests clinic-level prescription rates, not whether HIV infections fall. Results may not transfer to clinics with different resources or patient populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,380 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Provider:≥ 18-years old * Provider: employed at HFH as a primary care provider * Provider: eligible to write prescriptions in the state of Michigan * Patient: ≥ 18 years old * Patient: have an appointment with a Henry Ford primary care clinic during the study period * Patient: have an EHR account * Patient: meet the indications for PrEP Exclusion Criteria: * Provider: not a HFH primary care provider * Provider: does not have prescribing privileges in the state of Michigan * Patient: currently prescribed or taking PrEP * Patient: living with HIV
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Henry Ford Health
Detroit, Michigan, 48202, United States
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