Nasal spray showdown: which sedative works best for scared kids?
NCT ID NCT07180095
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 36 times
Summary
This study tests two different nasal sprays—dexmedetomidine and ketamine—to see which one better calms children aged 2 to 6 before surgery. Sixty kids will receive one of the two sprays, and researchers will measure how sleepy they get and how easily they separate from their parents. The goal is to find a needle-free way to reduce anxiety and make the surgical experience less stressful for children.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intranasal dexmedetomidine and intranasal ketamine
What this could lead to
If one drug works better, it could provide a safer, easier way to calm children before surgery without needles.
What could go wrong
This is an early-phase trial with only 60 children, so results may not apply to all kids. Both drugs can cause side effects like low blood pressure or slow breathing.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.