Can starting prehab early boost ovarian cancer outcomes?
NCT ID NCT07509814
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of prehabilitation (exercise, nutrition, and psychological support) for 225 women with advanced ovarian cancer. One group starts prehab early during chemotherapy, while the other starts just before surgery. The goal is to see if early prehab reduces surgical complications and improves how well the tumor responds to chemo.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- prehabilitation program (exercise, nutrition, and psychological support)
- What this could lead to
- If it works, this could show that starting prehabilitation earlier helps patients recover faster from surgery and respond better to chemotherapy.
- What could go wrong
- This is a relatively small, early-stage trial that hasn't started recruiting yet. The benefits seen in other cancers may not apply here, and the program requires significant patient commitment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 225 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients diagnosed with advanced ovarian cancer (FIGO III and IV) * Clinical indication of neoadjuvant chemotherapy followed by cytoreductive surgery * No contraindications for exercise training * Give written consent to participate Exclusion Criteria: * Patients diagnosed with advanced ovarian cancer scheduled for cytoredutive surgery followed by chemotherapy (no neoadjuvant) * Patients with deteriorated functional state (ECOG ≥2) or those with contraindication to exercise training (severe or unstable cardiorespiratory, metabolic, musculoskeletal or neurological conditions)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Clinic of Barcelona
Barcelona, Barcelona, 08036, Spain
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Hospital Universitario 12 de Octubre
Madrid, Madrid, 28041, Spain
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Hospital Universitario Germans Trias i Pujol
Badalona, Barcelona, 08916, Spain
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Hospital Universitario Navarra
Pamplona, Navarre, 31008, Spain
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Hospital Universitario y Politécnico La Fe
Valencia, Valencia, 46026, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could centralized surgery boost ovarian cancer survival?
- Real-World check: can a targeted ovarian cancer drug deliver outside clinical trials?
- Could a cheaper copy of a key chemo drug work just as well?
- Acupuncture with a jolt: could needles shield nerves from chemo?
- New cocktail aims to stall ovarian cancer
- Ovarian cancer surgery showdown: tumor removal vs. bowel resection