Could a few weeks of pre-surgery weight training boost hip replacement recovery?
NCT ID NCT07048080
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a supervised resistance exercise program, done for 2 weeks before and 12 weeks after total hip replacement, improves muscle mass and strength in adults aged 60 and older with severe hip osteoarthritis. Participants are randomly assigned to either the exercise program or standard rehabilitation. The study also looks at biological markers in blood and tissue samples to understand how the body responds to exercise.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- resistance exercise training
- What this could lead to
- If it works, this could show that a short course of strength training before and after hip replacement helps older adults recover muscle and function better than standard care.
- What could go wrong
- This is a small, early-stage trial with 70 participants, so results may not apply to everyone. The exercise program is demanding and may be hard for some to complete.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Individuals aged from 60 y and over. * 18.5 \< BMI \< 40 kg/m2. * Individuals on waiting list to undergo a unilateral elective surgery for Total Hip Replacement due to primary severe Osteoarthritis. Exclusion Criteria: * Individuals with severe OA in the contralateral hip. * Individuals who has been performing regular RET (2 or more times per week) in the previous 6 months. * Individuals who smoke. * Significant psychiatric or neurological disorders, with the use of acetylcholinesterase inhibitors, and untreated mood disorders or depressive pathology. * Neuromuscular or mobility disorders that prevent safe resistance training (debilitating arthritis, spasticity/rigidity, and paralysis), along with untreated metabolic disorders (such as uncontrolled systemic hypertension).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Universidad de La Frontera
Temuco, Cautin, 4780000, Chile
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