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Can exercise before cancer treatment improve outcomes?

NCT ID NCT06674889

Symptom relief Sponsor: UNC Lineberger Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether a personalized exercise and rehabilitation program given before cancer treatment (called prehabilitation) can help adults with cancer maintain their function and quality of life. Sixty participants will be randomly assigned to either receive the program or standard care. The study aims to see if this approach is practical and beneficial.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
prehabilitation program (exercise and specialty consultation)
What this could lead to
If successful, this could show that a tailored exercise program before cancer treatment helps patients feel better and function more independently.
What could go wrong
This is a very small pilot study with only 60 people, so results may not apply to everyone. It is testing feasibility, not yet proving effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Written informed consent obtained to participate in the study and HIPAA authorization for the release of personal health information. * Subjects are willing and able to comply with study procedures based on the judgement of the investigator. * Age ≥ 18 years at the time of consent. * The subject has been screened by the Central Oncology Navigation Program and referred to cancer care at the University of North Carolina Medical Center. * Answer "yes" to at least one of the following screening questions: 1. Does your health interfere with any of your activities of daily living (ADLs)? 2. Have you fallen, or do you feel unsteady while standing or walking? 3. Do you use durable medical equipment (DME)? 4. Are you interested in increasing the amount you exercise? Exclusion Criteria: * Inability to read and understand the English language. * Psychological or other disability resulting in the inability to provide informed consent. * Unstable medical comorbidity that precludes safe participation in an exercise program, in the judgment of the clinical investigator. * Prisoners and other institutionalized individuals.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Malignant tumor

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The N.C. Cancer Hospital

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

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