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Pregnancy and toxoplasmosis: new study aims to clarify risks for mothers and babies

NCT ID NCT05774496

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 76 women with congenital toxoplasmosis (a parasitic infection present from birth) to see if pregnancy increases the risk of eye inflammation (retinochoroiditis). Researchers checked eye exams done during pregnancy and after childbirth, comparing them to non-pregnancy periods. The goal is to provide better information to women about their own eye safety and the safety of their children.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could provide clearer guidance for women with congenital toxoplasmosis about the safety of pregnancy for themselves and their children.
What could go wrong
This is an observational study with only 76 participants, so results may not apply to all patients. It does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

76 people

The number who actually took part.

Started

May 2023

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The Lyon cohort is composed of 193 women suffering from a congenital toxoplasmosis confirmed at their birth in the parasitology and mycology unit of the La Croix-Rousse hospital, and they have been tracked since then.

Ages

21 to 50 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being a woman * Born before March 2022 * Suffering from congenital toxoplamosis Exclusion Criteria: * Refusal to give informed consent * Any condition that would limit the ability of the patient to give consent * Psychiatric cares * To be deprived of liberty * To be under administrative supervision

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Conditions

The condition(s) this trial relates to.

chorioretinitis congenital toxoplasmosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Congenital toxoplasmosis Retinochoroiditis

Contacts and locations

Locations

  • Service de parasitologie et mycologie médicale

    Lyon, 69004, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.