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Pre-Surgery hydration strategy cuts blood pressure drop risk

NCT ID NCT06231472

Prevention Sponsor: Mustafa Burgac Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving patients a personalized amount of IV fluids before surgery could prevent dangerously low blood pressure after anesthesia. 110 women undergoing gynecological pelvic surgery were randomly assigned to receive either weight-based fluids or standard fasting. The results showed that preemptive fluid therapy reduced the risk of post-induction hypotension.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

110 people

The number who actually took part.

Started

May 2022

Finished

Nov 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Gynaecological pelvic surgery planned for patients aged 18 years and over * Patients with an American Society of Anaesthetists score of 1-2-3 Exclusion Criteria: * Unstable haemodynamics (persistent hypotension preventing extubation at the end of surgery, arrhythmia, ejection fraction (EF) \< 40%), * Valvular heart disease, * Cardiac pacing, * Obesity (BMI \>35), * Chronic obstructive pulmonary disease (COPD), * Increased intrabdominal pressure, * Open wound at the US site, * Preoperative severe hypertension (systolic blood pressure \>180 mmHg, diastolic \>110 mmHg), * Use of angiotensin II receptor blockers (ARB), angiotensin coverting enzyme inhibitor (ACE-I) * Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

Hypovolemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypovolemia

Contacts and locations

Locations

  • Istanbul Professor Doctor Süleyman Yalçın City Hospital

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.