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Blood test may forecast stroke severity

NCT ID NCT07471061

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether certain blood test results can help predict how severe a stroke is and how well a person might recover. Researchers will check three different ratios in the blood of 60 adults with acute ischemic stroke. The goal is to see if these simple, routine tests can give doctors early clues about a patient's condition and future recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study will include adult patients (≥18 years) diagnosed with acute ischemic stroke, confirmed clinically and by neuroimaging, who present to the hospital within 24 hours of symptom onset. Patients with hemorrhagic stroke, active infection, chronic inflammatory diseases, malignancy, severe liver or kidney disease, or those receiving immunosuppressive therapy will be excluded. All participants will undergo routine blood tests to calculate monocyte-to-albumin, neutrophil-to-albumin, and total leukocyte-to-albumin ratios. Stroke severity will be assessed at admission using the NIH Stroke Scale, and functional outcome will be evaluated during follow-up using the Modified Rankin Scale.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (≥ 18 years old) admitted with a diagnosis of acute ischemic stroke confirmed by brain imaging (CT or MRI). * Admission within a defined time window from stroke onset (e.g., within 48 hours) to capture acute inflammatory response. * Availability of complete blood count (CBC) with differential and serum -albumin levels at admission. * Informed consent obtained from the patient or their legal representative. Exclusion Criteria: * Patients with hemorrhagic stroke or transient ischemic attack (TIA). * Patients with previous history of ischemic stroke. * Patients who accepted intravenous thrombolysis (IV tPA) and or mechanical thrombectomy. * Pre-existing inflammatory or autoimmune diseases (e.g., rheumatoid arthritis, lupus, inflammatory bowel disease) that could influence monocyte count or albumin levels. * Active infections (bacterial, viral, fungal) at admission. * Severe liver or kidney disease affecting albumin synthesis or catabolism. * Hematological disorders affecting white blood cell counts. ⚫ Patients on immunosuppressive therapy or corticosteroids. * Patients with known malignancy * Lack of complete blood count (CBC) with differential and serum albumin levels at admission. * Patients who received blood transfusions before blood sampling. * Patients with other acute severe medical conditions that significantly impact inflammatory markers (e.g., sepsis, major trauma).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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How to take part

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  1. The official record

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More trials for these conditions

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