Blood test may forecast stroke severity
NCT ID NCT07471061
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether certain blood test results can help predict how severe a stroke is and how well a person might recover. Researchers will check three different ratios in the blood of 60 adults with acute ischemic stroke. The goal is to see if these simple, routine tests can give doctors early clues about a patient's condition and future recovery.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will include adult patients (≥18 years) diagnosed with acute ischemic stroke, confirmed clinically and by neuroimaging, who present to the hospital within 24 hours of symptom onset. Patients with hemorrhagic stroke, active infection, chronic inflammatory diseases, malignancy, severe liver or kidney disease, or those receiving immunosuppressive therapy will be excluded. All participants will undergo routine blood tests to calculate monocyte-to-albumin, neutrophil-to-albumin, and total leukocyte-to-albumin ratios. Stroke severity will be assessed at admission using the NIH Stroke Scale, and functional outcome will be evaluated during follow-up using the Modified Rankin Scale.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (≥ 18 years old) admitted with a diagnosis of acute ischemic stroke confirmed by brain imaging (CT or MRI). * Admission within a defined time window from stroke onset (e.g., within 48 hours) to capture acute inflammatory response. * Availability of complete blood count (CBC) with differential and serum -albumin levels at admission. * Informed consent obtained from the patient or their legal representative. Exclusion Criteria: * Patients with hemorrhagic stroke or transient ischemic attack (TIA). * Patients with previous history of ischemic stroke. * Patients who accepted intravenous thrombolysis (IV tPA) and or mechanical thrombectomy. * Pre-existing inflammatory or autoimmune diseases (e.g., rheumatoid arthritis, lupus, inflammatory bowel disease) that could influence monocyte count or albumin levels. * Active infections (bacterial, viral, fungal) at admission. * Severe liver or kidney disease affecting albumin synthesis or catabolism. * Hematological disorders affecting white blood cell counts. ⚫ Patients on immunosuppressive therapy or corticosteroids. * Patients with known malignancy * Lack of complete blood count (CBC) with differential and serum albumin levels at admission. * Patients who received blood transfusions before blood sampling. * Patients with other acute severe medical conditions that significantly impact inflammatory markers (e.g., sepsis, major trauma).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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