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Brain games reveal how kids with autism learn language

NCT ID NCT06332144

Knowledge-focused Sponsor: Northeastern University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether the ability to learn patterns (called statistical learning) can predict how well first-graders with autism and their non-autistic peers improve their language and reading skills over three months. Forty-one children completed language tests and computer games inside and outside an MRI scanner. The goal was to understand how the brain picks up language patterns and whether this differs between autistic and non-autistic children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

41 people

The number who actually took part.

Started

Jan 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

72 to 90 months

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * current first grader (6;0 - 7;6) * Geographically located within the Greater Boston Metropolitan Area * Native English speakers * Normal hearing * Normal or corrected vision Inclusion criteria for children with ASD (N = 25): * Children with a professional diagnosis of autism according to expert clinical judgment * Capable of speaking sentences with three or more words * Social Communication Parent Questionnaire score \> 15 * Autism diagnosis confirmed by ADOS Inclusion criteria for typically developing controls (N = 25): * Neurotypical: with no known cognitive, neurological, or psychiatric disorders * Social Communication Parent Questionnaire score \< 11 * Receive a score within 1 SD of the population mean for age on all assessments. Exclusion Criteria: * non-native speakers of English * More than 30 hours of exposure to a language other than English per week * history of brain injuries and head injuries * intellectual disability, mutism, motor delay, or developmental coordination disorder * metal in body * claustrophobic * history of prior neurosurgical procedure * substance abuse * signs of increased intracranial pressure

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder Literacy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autism spectrum disorder Language development Literacy

Contacts and locations

Locations

  • Boston University

    Boston, Massachusetts, 02215, United States

  • Northeastern University

    Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.