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New study reveals key clues to prevent dangerous calcium drop after thyroid surgery

NCT ID NCT07211581

Knowledge-focused Sponsor: Al Safwa University College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study of 123 patients looked at what factors predict low calcium levels after total thyroid removal. Researchers measured calcium and parathyroid hormone (PTH) levels before and after surgery. They found that a low PTH level after surgery is a strong warning sign for developing hypocalcemia. The goal is to help doctors identify at-risk patients early.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify patients at risk for low calcium after thyroid surgery, allowing earlier treatment.
What could go wrong
This is an observational study, not a treatment trial. It only identifies risk factors and does not test a new therapy or intervention.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

123 people

The number who actually took part.

Started

Sep 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

A total of 123 patients who underwent total thyroidectomy for various thyroid diseases were included in the study, performed by a group of surgeons.

Ages

21 to 76 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. patients requiring total thyroidectomy. 2. age between 18-75 years old 3. both gender 4. no co-existing disease. Exclusion Criteria: 1\. previous hemithyroidectomy, lobectomy, resection of the parathyroid gland. 2. 2. patients with missing laboratory data, previous subtotal thyroidectomy. 3\. diagnosed pathology of the parathyroid gland

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Conditions

The condition(s) this trial relates to.

Hypocalcemia hypoparathyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypocalcemia after total thyroidectomy

Contacts and locations

Locations

  • Mustaqbal University

    Sfax, Safx, 54001, Tunisia