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Brain scans and pain tests may foretell chronic pain after hysterectomy

NCT ID NCT02025153

Knowledge-focused Sponsor: KK Women's and Children's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study looks at whether certain tests—like brain imaging, pain sensitivity measurements, and psychological questionnaires—can help predict which women will develop long-term pelvic pain after a hysterectomy. Researchers will follow women undergoing hysterectomy for benign conditions and compare those who develop chronic pain with those who don't. The goal is to understand the mechanisms behind the transition from acute to chronic pain, which could lead to better prevention strategies in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pain testing (physical, psychological, genetic, and brain imaging assessments)
What this could lead to
If successful, this could help identify women at higher risk for chronic pain after hysterectomy, enabling earlier interventions.
What could go wrong
This is an observational study, so it won't test a treatment. The findings may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

216 people

The number who actually took part.

Started

Sep 2013

Finished

Jun 2017

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Anthropometric profile within the following range: age 21-70 yr, American Society of Anesthesiology status I and II women * Benign condition such as fibroids or adenomyosis * Abdominal or laparoscopic hysterectomy Exclusion Criteria: * Vaginal hysterectomy * being pelvic pain * Failure to adequately determine tonic heat stimulation and mechanical temporal summation * History of drug dependence or recreational drug use * Allergy to any study drugs

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome inherited disease susceptibility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anaesthesia Chronic pain Genetics predisposition

Contacts and locations

Locations

  • KK Women's and Children's Hospital

    Singapore, 229899, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.