Gut microbes may hold key to better cancer therapy
NCT ID NCT07263620
First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 28 times
Summary
This study looks at whether bacteria inside digestive system tumors can help predict how well a patient will respond to chemotherapy before surgery. Researchers will analyze tumor samples from 90 patients with stomach, colon, pancreatic, or esophageal cancer. The goal is to develop a test that identifies who will benefit most from neoadjuvant therapy, potentially sparing others from unnecessary side effects.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Patients with esophageal, pancreatic, gastric, or colorectal cancer who are scheduled to receive neoadjuvant therapy
RECRUITINGTianjin, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple test using gut bacteria to predict which patients will benefit from chemotherapy before surgery, personalizing cancer treatment.
What could go wrong
This is an early exploratory study with only 90 participants, so results may not apply to all patients. It is observational, meaning it does not test a new treatment, and the findings may not lead to immediate clinical changes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.