AI could help decide best treatment for ovarian cancer
NCT ID NCT06017557
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether artificial intelligence (AI) can analyze videos from a keyhole surgery (laparoscopy) to predict if ovarian cancer tumors can be completely removed. The goal is to help doctors choose the best treatment plan—surgery first or chemotherapy first—for each patient. About 151 women with advanced ovarian cancer will take part.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Artificial intelligence (AI) and machine learning software
- What this could lead to
- If successful, this could lead to a more accurate, automated way to decide whether ovarian cancer patients should have surgery first or chemotherapy first, improving treatment outcomes.
- What could go wrong
- This is a small pilot study, so the AI model may not be accurate enough yet. The results may not apply to all hospitals or patients, and the technology needs further validation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 151 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients treated at Fondazione Policlinico Gemelli Hospital, Rome Italy, Trillium -Credit Valley Hospital, Mississauga, Ontario and Princess Margaret Cancer Centre, Toronto, Canada * Patients fit for cytoreductive surgery * Patients with a primary diagnosis of suspect Stage III-IV ovarian cancer * Patients selected for interval cytoreductive surgery after NACT Exclusion Criteria: * Patients with pre-operative Stage I-II disease confined to the pelvis * Patients unfit for surgery * Lack of information about patients' surgical outcomes and clinicopathological characteristics * LGSOC, Clear cell and mucinous, non-epithelial histologic subtypes (if available)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC Ginecologia Oncologica
RECRUITINGRoma, 00168, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Microchip implanted in tumors could personalize ovarian cancer treatment
- New antibody combo shows promise for tough ovarian cancer
- Ovarian cancer immune cells under microscope in terminated study
- New vaccine combo aims to outsmart ovarian cancer resistance
- Pre-Surgery boot camp for cancer patients shows promise