Can a tailored home exercise program help lung cancer patients? new study aims to find out
NCT ID NCT06945484
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study is testing whether a personalized exercise regimen, delivered via telehealth, is feasible and safe for people with stage II or III non-small cell lung cancer who are receiving chemotherapy or immunotherapy and surgery. Twenty participants will follow a home-based program that includes mobility, aerobic, and resistance exercises, with one supervised session per week. The main goals are to see if patients can stick with the program and if it is safe, not yet to measure health benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Precision Exercise Regimen for Cancer Care (PERCC) - a personalized home-based exercise program delivered via telehealth
- What this could lead to
- If successful, this could show that a tailored exercise program is practical and safe for lung cancer patients, paving the way for larger studies to improve physical function and quality of life.
- What could go wrong
- This is a very small pilot study (20 participants) focused only on feasibility and safety, not on whether exercise actually improves health outcomes. Results may not apply to all lung cancer patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ages 18 and older at time of diagnosis * Patient diagnosed with stage II and III non-small cell lung cancer (NSCLC) * Patient receives either neoadjuvant chemotherapy or immunotherapy and surgery * Patient able to follow direction and complete questionnaires in English or Spanish * Patient agrees to complete the PERCC intervention Exclusion Criteria: * Morbidly obese (BMI \>40 kg/m2 ) or anorexic (BMI \<17.5 kg/m2 ) * Abnormalities on screening physical exam per study physicians or physical therapist to contraindicate participation in exercise program compliance * Alcohol or drug abuse, significant mental or emotional problems that would interfere with compliance (assessed by NCCN Distress Thermometer) * Patient scheduled to receive single modality cancer treatment (unimodal therapy), scheduled to begin treatment within 2 weeks of the pre-treatment clinic visit, or for whom treatment has already started
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
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University of Texas Medical Branch at Galveston
RECRUITINGGalveston, Texas, 77555, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Immunotherapy before lung surgery shows promise in early trial
- New immunotherapy combo aims to improve lung cancer outcomes
- Can a tailored drug cocktail beat lung cancer recurrence?
- New drug combo aims to wipe out lung cancer before surgery
- New combo therapy aims to shrink lung tumors before surgery