Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Prebiotic fiber and exercise may ease inflammation in kidney patients

NCT ID NCT03689569

Disease control Sponsor: Springfield College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking a prebiotic fiber (resistant starch) and doing moderate aerobic exercise for 16 weeks could reduce inflammation and improve blood vessel health, thinking, and mood in people with stage 3-4 chronic kidney disease. 68 patients were randomly assigned to receive the prebiotic or a placebo, with some also exercising. The goal was to see if these lifestyle changes could help manage the disease before dialysis is needed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
resistant starch (a type of prebiotic fiber)
What this could lead to
If it works, this could point toward a simple, non-drug way to manage inflammation and slow kidney disease progression.
What could go wrong
This is a small, early-stage study with only 68 participants. Results may not apply to everyone, and the benefits of prebiotics and exercise may be modest or hard to separate from other factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

68 people

The number who actually took part.

Started

Sep 2018

Finished

May 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * stage 3-4 of CKD (GFR 15-59 ml/min/1.73m2), * ages of 30-75 years old, * Must be capable of complying with and following the study protocol(diet and exercise) * Must be capable of independently giving informed consent Exclusion Criteria: * kidney transplant * currently in a structured exercise program * on antibiotic therapy within the last month * On a probiotic or prebiotic supplement within the last month * a GI disorder that prohibits the use of resistant starch (ie. high-amylose corn starch, which resists digestion * HIV positive * gastric by-pass surgery * clostridium difficile * marijuana user * lupus * rheumatoid arthritis * Hepatitis C * Post-traumatic stress disorder * deep vein thrombosis * pancreatitis

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chronic kidney diseases are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney diseases

Contacts and locations

Locations

  • Springfield College

    Springfield, Massachusetts, 01109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.