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Nose spray before surgery may ease behavior woes in kids with autism

NCT ID NCT07324057

First seen Jan 07, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This study tests whether giving a sedative nose spray (dexmedetomidine or esketamine) before anesthesia can reduce negative behavior changes—like sleep problems, anxiety, or eating issues—in children with autism after surgery. About 234 children aged 2-12 will be randomly assigned to receive one of the two medicines or a saltwater spray. Researchers will check for behavior changes at 1, 7, and 30 days after surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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